Receptor Tyrosine Kinase Signaling
About the Lecture
The lecture Receptor Tyrosine Kinase Signaling by Kevin Ahern, PhD is from the course Hormones and Signal Transduction. It contains the following chapters:
- Receptor Tyrosine Kinase Signaling
- Means of Activation
- Insulin Receptor
Included Quiz Questions
Which statement regarding receptor tyrosine kinases (RTKs) is true?
- They autophosphorylate on binding their hormone.
- They are active primarily as monomers.
- They remove phosphate from proteins.
- They do not regulate cell proliferation.
Which statement regarding phosphorylation of tyrosines on receptor tyrosine kinases (RTKs) is true?
- It requires dimerization.
- It can occur on the outside or inside of the cell.
- It turns off the signaling system.
- SH2 domains have no role to play.
Which statements regarding the signaling complex of receptor tyrosine kinases (RTKs) are true? Select all that apply.
- It has proteins that bind to phosphotyrosines.
- It involves the activation of intranuclear receptors.
- It transmits signals from the inside of the cell to the outside of the cell.
- It has proteins with SH2 domains.
- It communicates the message to the rest of the cell.
Which statement regarding insulin signaling is true?
- It activates phosphoprotein phosphatase.
- It activates the cyclic AMP pathway.
- It causes blood glucose levels to rise.
- Insulin signaling occurs in the same manner as epinephrine signaling.
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Author of lecture Receptor Tyrosine Kinase Signaling
Kevin Ahern, PhD
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I have taken biochem as an undergrad, grad. and post grad and I've never had anyone explain things as clearly. Dr. Ahern is one of the best teachers I've ever encountered. Thank you!
