Nucleoside Analogs and Deoxyadenosine Analogs
About the Lecture
The lecture Nucleoside Analogs and Deoxyadenosine Analogs by Kevin Ahern, PhD is from the course Purine and Pyrimidine Metabolism.
Included Quiz Questions
Which of the following is true regarding nucleoside analogs used in therapeutics?
- They are commonly competitive inhibitors of nucleotides when present in cells.
- They are commonly partial agonists of nucleotides when present in cells.
- Nucleotides move into cells more easily than these nucleoside analogs.
- These analogs are dephosphorylated once they enter the cell.
- These analogs cannot be phosphorylated because of their structure.
Nucleoside and nucleotide analogs commonly used as anti-viral therapeutic drugs to prevent what?
- Viral replication in the infected cells
- Viral adhesion to the cell surface receptors present on the outer surface of the cell membrane
- Viral replication by halting the movement of ribosomes
- Viral replication by halting the assembly of viral proteins
- Viral replication by facilitating the formation of defected viral protein coats
What is a benefit of nucleoside analogs?
- They readily cross the cell membrane.
- They readily cross the blood-brain barrier.
- They are excreted through the spleen.
- They are filtered through the duodenum.
- They have an unknown half-life.
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Author of lecture Nucleoside Analogs and Deoxyadenosine Analogs
Kevin Ahern, PhD
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