Medications for Peptic Ulcer Disease (PUD): In a Nutshell (Nursing)

00:00 Okay, so peptic ulcer disease are these open sores that develop on your stomach lining or in your small intestine.

00:06 So they can be in your stomach or your duodenals, so you'll see that duodenal ulcers.

00:12 They can lead to perforation and GI bleed in the worse case scenario.

00:17 Most common causes of peptic ulcer disease are H.Pylori - that nasty bug that can hide.

00:22 NSAIDS (Non Steroidal Anti Inflammatory Drugs), exposure to gastric acid and smoking or alcohol.

00:31 Antibiotics, H2 receptor antagonists, PPI's, mucosal protectants and antacids are full complete treatment plan for peptic ulcer disease.

00:42 So let's not fly by that too quickly.

00:44 When you're thinking through those medications, I want you to ask yourself, "Why?" So, why would somebody with peptic ulcer disease be on antibiotics? How many antibiotics should they be on? Remember we want them on a minimum of two antibiotics.

01:02 See if you can list at least two antibiotics that we studied in this video presentation.

01:09 Why would a patient be on H2 receptor antagonists? Because they'll help suppress gastric acid secretion.

01:18 Why would a patient with peptic ulcer disease be on PPI's? Well because they're the best at suppressing gastric acid but remember they come with a few really scary risk factors.

01:32 Why would someone with peptic ulcer disease be on mucosal protectants? Because that will actually protect and coat that sore in the stomach lining.

01:44 Why would a patient with peptic ulcer disease be on antacids? Because that will help neutralize gastric acid in the moment.

01:54 Look at all of those meds that we used and I wanna be sure that you have a complete list in your head.

02:00 That will help you be focused in knowing what we use to treat peptic ulcer disease in a complete way.

02:06 Now there is a breath test for H. Pylori and if we had a pick from those three options, I am sure we'd rather take a breath test than the serum or the biopsy option.

02:16 PPI's have the most serious list of possible side effects.

02:21 Everything from fractures, pneumonia to developing C. diff.

02:25 Remember patients with chronic kidney disease are extremely at risk and even if your patient doesn't have chronic kidney disease, it may develop if they take PPI's for a long period of time.

02:36 Also can pose a risk for gastric cancer.

02:39 And when you do stop at PPI, you can have this horrible rebound acid secretion which can make a big problem for your patient.

02:47 So you'll have to come up with some type of alternate treatment plan as the patient is weaning off with PPI's.

02:53 Than you for watching our video today on Peptic Ulcer Disease.