Lectures

Largest Known Viral Genomes – Introduction to Viruses (Virus Diseases)

by Vincent Racaniello, PhD
(1)

Questions about the lecture
My Notes
  • Required.
Save Cancel
    Learning Material 2
    • PDF
      Slides 04 Viruses MicrobiologyAdvanced.pdf
    • PDF
      Download Lecture Overview
    Report mistake
    Transcript

    00:00 that we just said are not in genomes will eventually be found to be there as well.

    00:01 Let's take a look at some of the extremes of viruses, the biggest and the smallest known virus genomes, just to give you an idea of how many nucleotides and proteins are in these.

    00:10 The biggest virus genome identified to date is from a virus called Pandoravirus salinus, it's over 2.4 million base pairs of DNA long. It encodes 2,541 proteins. This is absolutely huge, the average virus is far, far smaller than this. And this goes down a list of genomes to what is a relatively small genome of 610,000 for pithovirus sibericum encoding 467 proteins.

    00:43 So these are the top 10 or 12 genomes, according to size, ranging from two and a half million down to 600,000 base pairs. These are really the giants in the virus world. At the other extreme are the small virus genomes, let's take a look at some of those. The smallest known viral genome is from an agent called a viroid. It's 120 nucleotides of circular RNA and it encodes no proteins. These are typically plant pathogens that enter plant cells and cause disease without encoding any proteins, really, really remarkable and again, slightly larger genome, 4,000 bases in length, encoding seven proteins and in between these extremes you can see there's some viruses that encode just one or two proteins. So truly the virus world is remarkable, there is a huge range, it is quite different from say, Homosapiens, where our genomes are more or less the same length.


    About the Lecture

    The lecture Largest Known Viral Genomes – Introduction to Viruses (Virus Diseases) by Vincent Racaniello, PhD is from the course Viruses.


    Included Quiz Questions

    1. Pandoravirus
    2. Mimivirus
    3. Parvovirus
    4. Pox virus
    5. Hepatitis B virus
    1. 2.4 million base pairs
    2. 3.4 million base pairs
    3. 4.4 million base pairs
    4. 5.5 million base pairs
    5. 6.2 million base pairs

    Author of lecture Largest Known Viral Genomes – Introduction to Viruses (Virus Diseases)

     Vincent Racaniello, PhD

    Vincent Racaniello, PhD


    Customer reviews

    (1)
    5,0 of 5 stars
    5 Stars
    5
    4 Stars
    0
    3 Stars
    0
    2 Stars
    0
    1  Star
    0