Clinical Application of Creatinine

by Carlo Raj, MD

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    Creatinine: all the different places that you might have to run to, to look for the relevant information of creatinine. It's all here. What does that mean? What is a normal mechanics of creatinine? What does it mean to you in terms of interpretation of creatinine so that you can help you diagnose your patient? Remember this is going to be part of your laboratory investigations and is it the only thing that you are going to use to confirm. No, but it is a darn important one. What is creatinine? We will begin. The breakdown product of the skeletal muscle and how often does that occur? All the time constitutively. Keep that in mind. Constant release into the blood stream. Once again because your muscles are breaking down you get it into your bloodstream. Remember as to what the normal levels of creatinine is? Well, I want you to think of 6 and 12. You double 6 and you get 12. It is 0.6 to approximately 1.2. Keep it simple. There is so many different things that you need to memorize, right? And a couple of things here and perhaps it may help you keep it mind, but 0.6 to 1.2. How does the kidney handle creatinine? Well, I want you to go into the plasma. I want you to go into afferent arteriole. I want you to arrive at the glomerulus and I want you to filter through. Does creatinine get filtered? Is it small enough for it to get filtered? It is. So it gets filtered. Correct. Okay? Next. As it gets filtered, you will continue through your glomerular capillaries and you end up on the efferent arteriole, are you there? and you continue through the peritubular capillaries. We call this what? vasa recta and you tell...

    About the Lecture

    The lecture Clinical Application of Creatinine by Carlo Raj, MD is from the course Renal Pathology. It contains the following chapters:

    • The Basics of Creatinine
    • Creatinine: Clinical Application
    • Creatinine Clearance
    • Causes of Increased and Decreased Ccr
    • Experimental Calculations of Renal Function

    Author of lecture Clinical Application of Creatinine

     Carlo Raj, MD

    Carlo Raj, MD

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