by Jeremy Brown, PhD

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    So the subject of this lecture is asthma, which is one of the common forms of airways disease that affects respiratory patients. When we talk about airways disease, we mean diseases that affect the conducting airways, the trachea, the major bronchi, and the bronchioles going down as far as the terminal bronchioles. We don’t mean diseases affecting the alveoli. These airways diseases, in general, will present with some form of airways obstruction. And that will be recordable when you do lung function test as obstructive lung function changes. They don’t tend to show many abnormalities on a chest X-ray. That is because the bronchi are not readily detectable on X-ray, and the changes we’re talking about are relatively small changes in multiple different parts of the airways rather than a single mass lesion as if you have a cancer, for example. There are a range of potential airways diseases. However, this subject is dominated by two airways disease; asthma and chronic obstructive pulmonary disease. COPD, this is a subject to the next lecture as really a smoking-related lung disease. In this lecture, I will concentrate largely on asthma. In addition, I will cover post-infective bronchial hyperactivity. At third lecture, we'll discuss other airways diseases, the causes of large airway obstruction, bronchiectasis, and allergic bronchopulmonary aspergillosis. A major thing about airways disease is that the obstruction that occurs can be described as reversible or irreversible. So the prevention of effective airflow can be reversed, in reversible disease, can be improved of treatment, whereas, with irreversible disease, it can’t be. That’s the broad distinction. There are of course patients in between with partially reversible airways disease, where the obstruction can be partially reversed but doesn’t get as good as normal. Largely speaking, asthma is a reversible airways disease, whereas, COPD is an...

    About the Lecture

    The lecture Asthma by Jeremy Brown, PhD is from the course Respiratory Medicine (Pulmonology): Advanced. It contains the following chapters:

    • Lower airways obstruction
    • Asthma - clinical history
    • Asthma - subtypes of disease and diagnosis
    • Asthma - treatment
    • Asthma - acute exacerbations
    • Asthma - complications

    Quiz for lecture

    Test your knowledge with our quiz for lecture Asthma.

    1. Reduced FEV1 and FVC with a ratio of FEV1 / FVC of less than 70%
    2. Reduced FEV1 and FVC with a ratio of FEV1 / FVC of greater than 80%
    3. Reduced FEV1 with an increased FVC
    4. An increased FEV1 with a reduced FVC
    1. Haemoptysis
    2. Symptoms that get worse after an viral upper respiratory tract infection
    3. No history of childhood asthma
    4. Waking in the middle of the night due to cough
    1. A peak flow recording that increases from 200 to 350 after a salbutamol nebuliser
    2. Peripheral blood eosinophilia
    3. A chest X ray showing no obvious radiological abnormalities
    4. Oxygen saturations of 89% on air
    1. A reduced PaCO2
    2. Bradycardia
    3. Reduced conscious level
    4. Inaudible breath sounds on auscultation of the chest

    Author of lecture Asthma

     Jeremy Brown, PhD

    Jeremy Brown, PhD

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    This is very well-explained! …
    By Peter R. on 30. April 2016 for Asthma

    This is very well-explained!