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African Trypanosomiasis

by Vincent Racaniello, PhD
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    00:00 this is a blood smear, so there are red blood cells present. First we will look at the African Trypanosoma. There are African and American Trypanosomes with very different outcomes.

    00:09 One of the African Trypanosomaes, Trypanosoma brucei gambiense. Let’s take a look at the distribution of this. You can see that these parasites are found largely in central Western Africa. Very specific place, nowhere else on the planet. Trypanosoma brucei gambiense.

    00:35 The other trypanosome present in Africa is Trypanosoma brucei rhodesiense. And let's take a look at the distribution of this parasite. Look it's very different, that's on the eastern coast of South Africa, very different from gambiense. These infections, these parasites, are spread by the Tsetse fly, the species glossina, these are very large flies, you can't tell from this photograph, an inch long, that can give you quite a nasty bite and deliver quite a serious disease. Among the African trypanosomiasis, the animal reservoirs are different for the East African and the West African parasites. The reservoirs for the East African parasites are game animals, like impalas, like this animal here is an impala, and other game animals. So these parasites exist in those reservoirs. The West African Trypanosoma has as reservoirs either humans or domestic animals like cattle. So the very distinct geographic distributions of these two different African Trypanosomes are a consequence of the distribution of the animal reservoir. In both cases they are spread by the same vector, the tsetse fly.


    About the Lecture

    The lecture African Trypanosomiasis by Vincent Racaniello, PhD is from the course Parasites.


    Included Quiz Questions

    1. Tsetse fly
    2. Male Anopheline mosquito
    3. Sporothrix Schenckii
    4. Ixodes Scapularis
    5. Sandfly
    1. Central Western Africa
    2. Central Eastern Africa
    3. Eastern coast of South Africa
    4. Western coast of South Africa
    5. East Africa

    Author of lecture African Trypanosomiasis

     Vincent Racaniello, PhD

    Vincent Racaniello, PhD


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